| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
|
3 | 10 | 0 | 3 | 16 |
|
7 | 10 | 7 | 21 | 45 |
| SF | BUF | |
|---|---|---|
| 16 | First downs | 29 |
| 300 | Total yards | 492 |
| 167 | Passing yards | 179 |
| 133 | Rushing yards | 313 |
| 60 | Total plays | 74 |
| 3 of 13 | Third down | 8 of 13 |
| 0 of 2 | Fourth down | 0 of 0 |
| 3–20 | Sacked | 3–0 |
| 1 | Turnovers | 2 |
| 6–52 | Penalties | 7–71 |
| 5, 41.8 avg | Punts | 3, 50.7 avg |
| 24:49 | Possession | 35:11 |
Arik Armstead Sacks Tyrod Taylor & Forces a Fumble on the Handoff! | 49ers vs. Bills | NFL
Colin Kaepernick Throws 53-Yard TD to Torrey Smith! | 49ers vs. Bills | NFL
LeSean McCoy Runs in 2 First-Half TDs! | 49ers vs. Bills | NFL
LeSean McCoy Knocked Down by Teammate to Stop TD on Huge Run! | 49ers vs. Bills | NFL
LeSean McCoy Ankle-Breaking Run Leads to Tyrod Taylor's 30-Yard TD Pass! | 49ers vs. Bills | NFL
Tyrod Taylor's 21-Yard Run Sets Up LeSean McCoy's 3rd TD of the Day! | 49ers vs. Bills | NFL
Mike Gillislee's Powerful 44-Yard TD! | 49ers vs. Bills | NFL
LeSean McCoy Explodes for 140 Yards & 3 TDs! (Week 6 Highlights) | 49ers vs. Bills | NFL
Every Colin Kaepernick Completion & Run from His 1st Start of Season | 49ers vs. Bills | NFL
49ers vs. Bills (Week 6) | Game Highlights | NFL
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